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Understanding Fully Human and Humanized Monoclonal Antibodies
Monoclonal antibodies (mAbs) are useful therapeutics for targeted treatments in oncology, autoimmune...
What is Antibody Pharmacokinetics?
Antibody pharmacokinetics (PK) is the study of how the body interacts with antibodies after administration,...
What is Single-Cell Antibody Sequencing?
Single-cell antibody sequencing is a technique for analyzing the genome of individual antibody-producing...
What is a VHH Library?
A VHH library refers to a collection of single-domain antibodies, also known as nanobodies or VHHs. These...
What is Affinity Maturation?
Affinity maturation is the process of improving antibody affinity and binding interactions to target...
What are Monoclonal Antibodies?
Monoclonal antibodies (mAbs) are produced from identical B lymphocytes, ensuring that they are homogenous...
Antibody Effector Functions
Antibodies are versatile molecules that perform a range of effector functions, many of which engage different...
Antibody Allotypes: Genetic Variation in Immunoglobulins
In addition to isotypes and subtypes, antibodies exhibit genetic variation known as allotypes, which...
Engineered Antibody Formats: A Historical Perspective
Modified versions of antibodies have been designed to improve certain properties or functionalities,...
Microfluidic Technology in Biotechnology
The use of microfluidics to precisely control fluid behavior in micro- and nano-environments has enabled...
What Is Phage Display?
Phage display leverages the natural biology of bacteriophages—viruses that specifically infect bacteria...
Understanding the Difference Between ADC Biosimilars and ADC Isotypes
What Are ADCs?
ADCs are complex biopharmaceuticals that consist of three key components:
Monoclonal...
The Future of Therapeutics: Fully Human Antibodies
Fully human antibodies offer distinct advantages in antibody drug development. They trigger minimal immune...
Immune Checkpoint Inhibitors and Antibody Therapeutics: A Paradigm Shift in Cancer Treatment
Cancer immunotherapy has emerged as a transformative approach in oncology, with immune checkpoint inhibitors...
High-Efficiency Expression and Production of Recombinant Antibodies in Chinese Hamster Ovary (CHO) Cells
Chinese hamster ovary (CHO) cells have emerged as the predominant expression system for producing recombinant...
Understanding the Value of Research-Use-Only (RUO) Biologics in Preclinical Studies
In the complex landscape of drug discovery and development, preclinical studies are instrumental in evaluating...
Transforming In Vivo Research with Bispecific Antibodies
Bispecific antibodies (BsAbs) offer unparalleled versatility and precision in targeting multiple antigens...
Antibody-Mediated Phagocytosis Against Cancer
A review by researchers from the University of Virginia highlights the role of antibody-dependent cellular...
Structure and Dynamics in Antibody Therapeutics Design (biointron.com)
The field of biotherapeutics has seen rapid advancements with antibodies and antibody-like formats emerging...
Antibody-Drug Conjugates: A Brief
Antibody-Drug Conjugates (ADCs) are a breakthrough in oncology, integrating the targeting precision of...
Combination Therapies and Synergistic Approaches
Combination therapies and synergistic approaches refer to the use of multiple treatments or interventions...
Custom Antibody Development: A Step-by-Step Guide
Antibodies are indispensable tools in both research and clinical diagnostics, serving as highly specific...
How Therapeutic Antibodies Are Produced: Antibody Engineering
The field of antibody engineering has made significant strides in creating molecules that are increasingly...
Epitope Characterization and its Importance in Antibody Therapeutics
The therapeutic efficacy of antibodies is closely related to their ability to recognize and bind specific...
Antibody Specificity and Selectivity for Precision in Research
Understanding the differences between antibody specificity and selectivity is essential for designing...
Using Recombinant Antibody Production to Create Antibodies
Recombinant antibody production is a revolutionary technology that has significantly impacted biomedical...
Differentiation into Plasma Cells: A Journey of Specialization
Following activation, a subset of B cells undergoes differentiation to become plasma cells. This transformation...
B Cell Activation: A Deeper Dive into the Signaling Symphony
Upon recognizing their specific antigen through the B cell receptor (BCR), B cells undergo a complex...
Sensitivity and Experimental Environments in Antibody Performance
Antibody-based assays are essential in biomedical research, providing the means to detect, quantify,...
Immune Checkpoint Inhibitors and Antibody Therapeutics: A Paradigm Shift in Cancer Treatment
Cancer immunotherapy has emerged as a transformative approach in oncology, with immune checkpoint inhibitors...
The Unique Origin of VHH Antibodies: Camelid-Derived Nanobodies
Antibody-based therapies provide highly specific treatments for various diseases. Among these, VHH antibodies,...
Research-Use-Only (RUO) Biologics for Antibody In Vivo Research
Biologics, particularly antibodies, have become indispensable in biomedical research and therapeutic...
Antibody Labeling
Antibody labeling is an invaluable tool for clinical and research experiments, allowing scientists to...
Harnessing Big Data: Databases in Antibody Engineering
Technological advancements in recent years, such as next-generation sequencing, have made it possible...
AI and Computational Approaches in Antibody Research
Artificial intelligence (AI) and computational methods are a powerful tool for antibody discovery and...
AI Deep Learning Models in Antibody Research
Although the incorporation of artificial intelligence (AI) in antibody research is still in its early...
How Therapeutic Antibodies Are Produced: Screening and Selection
Once potential therapeutic antibodies are engineered, they undergo rigorous screening and selection to...
How Therapeutic Antibodies Are Produced: Cell Line Development and Processing
Therapeutic antibodies have revolutionized treatment paradigms across a range of diseases, including...
Afucosylated Antibodies: Mechanism of Action and Therapeutic Applications
Afucosylated antibodies are characterized by the absence of fucose sugar residues on their Fc (fragment...
The Power of Computational Predictors: Antibody Developability
Before the road towards clinical trials, the developability properties of therapeutic antibodies need...
Multi-Payload Antibody–Drug Conjugates
Antibody–drug conjugates (ADCs) have emerged as a revolutionary class of targeted cancer therapies, combining...
Affinity Maturation
Affinity maturation refers to the process of improving antibody affinity and binding interactions to...
Core Functions of Antibodies
The core functions of antibodies within the immune system are highly diverse and important, serving as...
BIO 2024 – San Diego: Highlights and Event Recap
The BIO International Convention 2024 was held in San Diego, CA from June 3-6. It is the largest event...
What Are Antibody Mimetics?
Antibody mimetics, also known as non-immunoglobulin scaffolds, are engineered proteins designed to mimic...
Essentials of Antibody Production & Purification
Antibodies, also known as immunoglobulins, are like the body’s own defense soldiers made by our...
Technological Innovations in Antibody Production
The field of antibody production has witnessed significant technological advancements over the past years,...
VHH Library Generation
VHHs, also known as single-domain antibodies or nanobodies, are the smallest antigen-binding fragments...
Phage Display Technology
Phage display technology is a powerful technique for antibody discovery. It is often used to identify...
Antibody-Antibiotic Conjugates (AACs) in the Fight Against Bacterial Infections
The rapid rise of antimicrobial resistance (AMR) presents a critical challenge in modern healthcare....
Unlocking the potential of IVDs: exploring regulatory updates
Jonathan Ripley, IVD and MD consulting services director at IMed Consultancy discusses the role of IVDs,...
The Role and Development of TCR-like Antibodies in Cancer Immunotherapy
T-cell receptor (TCR)-like antibodies represent a novel and promising class of therapeutic agents that...
Deep Learning in Antibody Structural Modeling
Understanding the structures and functions is essential to designing an antibody for a specific goal....
Computational Design of Antibodies for Drug Discovery
The development of therapeutic antibodies has been significantly enhanced by advancements in computational...
10 Intriguing Facts About Antibody Production
The production of antibodies for research and therapeutic purposes is a sophisticated field that combines...
The Role of Antibody Production in Vaccination: From Development to Immune Response
Vaccination is one of the most effective tools in preventing infectious diseases. At its core, the success...
Navigating the Landscape of CAR-T Cell Engineering with Antibody Discovery
Chimeric antigen receptor (CAR)-T cell therapy is a revolutionary cancer treatment in which engineered...
Advanced Analytical Techniques for Antibody Characterization
The Evolution of Antibody Characterization
The field of antibody characterization has dramatically...
A Historical Overview of VHH Antibodies
VHH antibodies, also known as single-domain antibodies (sdAbs) or nanobodies, are a class of antibodies...
Transgenic Animals in Antibody Discovery
Transgenic animals are organisms genetically modified to contain one or more foreign genes, known as...
Muronomab: The First Approved Monoclonal Antibody
Muronomab-CD3, also known by its trade name Orthoclone OKT3, is historically significant as it was the...
Innovating Cancer Treatment: Bispecific Antibody Drug Conjugates
Bispecific antibody-drug conjugates (bsADCs) are an emerging class of therapeutics that combine the dual-targeting...
CACLP & CISCE 2024 Draw Global Attention to Innovations and Collaborations in IVD Industry
Chongqing, China – From 16 to 18 March 2024, the bustling halls of Chongqing International...
How the new In-Vitro Diagnostics Regulations are affecting the life sciences landscape
Could you please give our readers a brief overview of your role and your background?
I am the Vice...
8 Key Trends in the $106 Billion Worldwide IVD Market
OVID-19 created unprecedented demand for in vitro diagnostic expertise and products, and Kalorama Information’s...
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